Serene Leaf library
CBD Guides
What the trials measured — including the ones that found nothing. Doses, timing, interactions, and the questions the research has not answered.
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CBD for muscle recovery: four trials, three of them null
A single 60 mg dose after squats moved creatine kinase and squat 1RM slightly at 72 hours, and nothing at 24 or 48. Oral and topical…
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CBD for anxiety: one dose worked, two others did not
300 mg beat placebo before a public-speaking test, while 100 mg and 900 mg in that same study did nothing. A review of 11 trials couldn't…
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How much CBD to take: no established dose, only ranges
Sleep trials ran 25 mg to 300 mg an evening; retail labels start near 10–25 mg. The weight-based charts everywhere online have no trial behind them.
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CBN for sleep: the first sleep-lab trial missed its mark
Wake after sleep onset didn't move at 300 mg (−6.3 minutes, p = 0.29). Falling asleep was faster — in 20 people, for one night, at…
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CBD vs melatonin for sleep: neither is an insomnia fix
AASM advises against melatonin for sleep onset or maintenance, backing timed doses only for circadian disorders. Cannabidiol at 150 mg matched placebo.
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CBD and sleep: it is not the sedative the label implies
Most studies in one systematic review reported some benefit; 150 mg of pure cannabidiol nightly matched placebo on insomnia severity and time to drop off.